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Ascorbic acid precursors to maximize topical and local antiaging activity: further insights 2024

Ascorbic acid precursors to maximize topical and local antiaging activity: further insights 2024

Andrea Tognelli, Pharmacist – Florence News from experimental and clinical research The journal International Immunopharmacology (1) of April 2024 published an article on the superiority of ascorbyl palmitate , compared to ascorbic acid, to carry out a powerful selective inhibition activity of the NLRP3 inflammasome.

Latest findings on mitochondria activity, skin cells, targets and results of mitochondrial antiaging

Latest findings on mitochondria activity, skin cells, targets and results of mitochondrial antiaging

By Andrea Tognelli, pharmacist – Florence Introduction (1, 2) More than 10,000 articles published in international scientific journals and archived in the biomedical database PubMed during the year 2023 have been dedicated to mitochondria. In November ’23, the influential journal Nature also delved into very

Peri- and post-menopause: news on the benefits of targeted dietary supplementation

Peri- and post-menopause: news on the benefits of targeted dietary supplementation

Andrea Tognelli, Pharmacist – Florence The menopausal transition includes changes at the level of the body’s cellular activities, affecting mitochondrial functions, the onset of oxidative stress, and a state of moderate chronic inflammation. These mutually related alterations have led scientific research to consider them an

Brain and Cognition: Neuroprotective Effects of Resveratrol

Brain and Cognition: Neuroprotective Effects of Resveratrol

Andrea Tognelli, Pharmacist Dietary supplementation with Resveratrol (RSV) has demonstrated interesting neuroprotective activities in a growing number of experimental and clinical researches, due to an effective specificity of action on mitochondrial activities, and other biomechanisms concerning brain structures. New research has in fact highlighted the

HAIR LOSS: Current topics on oxidative stress and the role of antioxidants

HAIR LOSS: Current topics on oxidative stress and the role of antioxidants

Andrea Tognelli, Pharmacist A growing scientific literature highlights the role of oxidative stress, inflammatory processes and mitochondrial dysfunction in the onset of various forms of hair loss. Experimental and clinical research opens new scenarios on the contribution deriving from integration with molecules with antioxidant and

Resveratrol: supplementation in peri- and post-menopause for the skin and much more

Resveratrol: supplementation in peri- and post-menopause for the skin and much more

Article by Andrea Tognelli Estrogen decline and skin health The lowering of estrogen levels in the post-menopause also causes changes at the skin level, for example: loss of collagen, elastin, alterations in the functions of fibroblasts and vascularization, which determine xerosis, wrinkle formation, and atrophy.